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23/02/2012
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Case Report: Adalimumab Lowers Sperm Count
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Adalimumab therapy was associated with a significant decrease in sperm count in a 35-year-old man who had taken the biologic for 3 years as treatment for ankylosing spondylitis, according to a case re...
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17/02/2012
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Vitamin E Supplements Linked to Increase in Prostate Cancer Risk
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SAN FRANCISCO (EGMN) – Healthy middle-aged and older men who take vitamin E supplements have an increased risk of prostate cancer, although the risk takes some time to emerge, suggests an update of th...
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16/02/2012
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Costs Don’t Always Match Outcomes of Prostate Cancer Treatments
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SAN FRANCISCO (EGMN) – Two new U.S. studies involving more than 150,000 older men with prostate cancer are likely to add to the intense debate about the optimal treatment for early disease, especially...
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14/02/2012
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Everolimus Shrinks Angiomyolipomas from Tuberous Sclerosis Complex
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SAN FRANCISCO (EGMN)–Everolimus is efficacious and safe for shrinking renal angiomyolipomas and reducing the formation of new ones in patients having the genetic disorder tuberous sclerosis complex or...
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11/02/2012
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Mild CKD Ups Risks of Renal, Urothelial Cancers
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SAN FRANCISCO (EGMN)–Chronic kidney disease, even on the milder end of the spectrum, is an independent risk factor for urinary cancers and may therefore be useful for targeting screening, the results ...
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09/02/2012
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U.S. Agency Rejects Denosumab Against Bone Metastasis in Prostate Cancer
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SILVER SPRING, MD. (EGMN) – A U.S. Food and Drug Administration advisory panel voted 12 to 1 on Feb. 8 that denosumab did not have a favorable risk-benefit profile as a treatment to reduce the risk of...
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08/02/2012
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FDA Questions Earlier Denosumab Use in Prostate Cancer
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The Food and Drug Administration questions whether an additional indication for denosumab to delay bone metastases in men with castrate-resistant prostate cancer who are at high risk for such metastas...
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08/02/2012
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Kidney Cancer Patients May Need Higher Axitinib Dose
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SAN FRANCISCO (EGMN)–Some patients with metastatic renal cell carcinoma may need a higher-than-standard dose of the newly approved antiangiogenic agent axitinib to achieve optimal benefit, according t...
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07/02/2012
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ALSYMPCA Trial: Radium-223 Prolongs Life in Some Prostate Cancers
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SAN FRANCISCO (EGMN) – Radium-223 chloride, the first alpha particle–emitting bone-targeted agent, is efficacious and safe for treating men with bone metastases of castration-resistant prostate cancer...
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04/02/2012
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MDV3100 Cuts Risk of Death in Advanced Prostate Cancer
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SAN FRANCISCO (EGMN) – MDV3100, new oral inhibitor of androgen receptor signaling, reduces the risk of death by more than a third after a failure of docetaxel chemotherapy in men with progressive cast...
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01/02/2012
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ASCO GU to Spotlight Prostate Cancer Drugs MDV3100 and Radium-223
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The 2012 Genitourinary Cancers Symposium, to be held Feb. 2-4, will feature potentially practice-changing data on two novel agents – MDV3100 and radium-223 chloride – in prostate cancer.• Results of t...
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30/01/2012
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Study Supports Oral Antibiotics for Acute Pyelonephritis
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The incidence of renal scarring did not differ significantly in children with acute pyelonephritis and scintigraphy-documented acute lesions who were treated with oral antibiotics, compared with those...
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24/01/2012
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Excitement Builds for Renal Denervation in Hypertension
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MIAMI BEACH (EGMN) –The U.S. pivotal trial assessing renal denervation for blood pressure reduction began in October and a report on its final results won’t appear until next year, but excitement base...
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20/01/2012
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Meta-Analysis Outlines Lithium Toxicity Profile
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Lithium is associated with an increased risk of reduced urinary concentrating ability, hypothyroidism, hyperparathyroidism, and weight gain, but, despite widespread belief to the contrary, it may not ...
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19/01/2012
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First U.S. Fibromuscular Dysplasia Registry Yields New Clues
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MIAMI BEACH (EGMN) – The mystery shrouding fibromuscular dysplasia, a clinically important and surprisingly prevalent vascular disease of unknown etiology, began to lift with initial findings from 339...
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10/01/2012
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Rheumatoid Arthritis Linked to Erectile Dysfunction
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Men with rheumatoid arthritis have a two-thirds greater risk of developing erectile dysfunction than men without the disease, based on the results of the first study to show such an association.The od...
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07/01/2012
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Prostate Cancer Deaths: Annual Screen Not Superior to Usual Care
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After 13 years of follow-up, men who underwent annual screening for prostate cancer were no less likely to die of prostate cancer than were men who received usual care and opportunistic screening.Cumu...
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21/12/2011
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Urinary Dysfunction Stands Out on Retigabine’s Safety Profile
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BALTIMORE (EGMN)–The safety profile for retigabine is generally consistent with that of other antiepileptic drugs, but data from studies in its evaluation process show that it also carries a novel, sm...
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14/12/2011
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Combining MRI With Prostate Ultrasound Biopsy Bests Biopsy Alone
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CHICAGO (EGMN)–Fusing MRI with real-time, three-dimensional ultrasound allows for more targeted prostate biopsies and finds additional cancers, compared with standard systematic biopsies.“This may lea...
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10/12/2011
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MRI Identifies Candidates for Prostate Cancer Surveillance
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CHICAGO (EGMN)–Multiparametric magnetic resonance imaging trumped national guidelines in correctly classifying patients with prostate cancer as candidates for active surveillance in a retrospective st...
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